Boletín de la Sociedad Geológica Mexicana

Volumen 68, núm. 1, 2016, p. 165-172

Short note

 

DNA structure and architecture in the chromosome and plasmid of hyperthermophilic organisms, a theoretical approach

Héctor G. Vázquez1, Arturo Becerra1,*

1 Facultad de Ciencias, Universidad Nacional Autónoma de México, Ciudad Universitaria, Delegación Coyoacán, 04510 CDMX, México.

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Abstract

Hyperthermophilic organisms have been recognized as an important element in the origin and early evolution of life on Earth, but also as a model for exobiological studies. Analyzing their molecular dynamics can help us understand this important lifestyle. In this study, using bioinformatic tools, the DNA composition in chromosomes and plasmids of hyperthemophilic organism were compared, and their structure, probable amino acid bias and DNA flexibility were analyzed. In some chromosomes and plasmids shows differential features of DNA flexibility and skews in mutation rate, which suggests that only some molecular elements show high values of variability, contrary to the proposal of the flexible genome theory.

Keywords: chromosome, plasmids, Quintana values, DNA twisting, codon usage, hyperthermophiles.


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